Figure 7
From: Interleukin-31 expression and relation to disease severity in human asthma
Immunohistochemical analysis of IL-31 receptor (IL-31RA and OSMR).
Immunohistochemical staining was performed to assess the expression of IL-31RA (A–D) and OSMR (E–H). (Magnification × 400, red arrows). Representative photomicrographs are presented from a healthy individual (A,E), patient with mild asthma (B,F), patient with severe asthma (C,G) and the corresponding isotypic control (D,H). The expression of IL-31RA and OSMR in patients with severe asthma were higher than those in controls and patients with mild asthma (I,K). Moreover, the relationships between the serum IL-31 levels and percentage (%) of cells expressing of IL-31RA and OSMR were assessed by Spearman’s rank correlation analysis (J,L). Data are presented as median with interquartile range. *p < 0.05, **p < 0.01, ***p < 0.001.
