Figure 1: An exo1∆ rqh1∆ double mutant exhibits a synergistic increase in sensitivity to MMS, HU and CPT. | Scientific Reports

Figure 1: An exo1∆ rqh1∆ double mutant exhibits a synergistic increase in sensitivity to MMS, HU and CPT.

From: The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks

Figure 1

(a) Spot assay comparing wild-type (FO656), exo1∆ (FO951), rqh1∆ (MCW1019) and exo1∆ rqh1∆ (FO1011) strains for sensitivity to a range of genotoxins. (b) Spot assay comparing wild-type (FO656), exo1∆ rqh1∆ (FO1011), exo1∆ rqh1K547A (MCW4029), exo1∆ rqh1K547R (MCW4030), rqh1K547A (MCW2453) and rqh1K547R (MCW2454) strains for sensitivity to CPT.

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