Figure 4: Female miR-155 KO mice on HFD did not have altered adipogenic or insulin sensitivity genes, but had reduced expression of inflammatory mRNAs in WAT. | Scientific Reports

Figure 4: Female miR-155 KO mice on HFD did not have altered adipogenic or insulin sensitivity genes, but had reduced expression of inflammatory mRNAs in WAT.

From: miR-155 Deletion in Female Mice Prevents Diet-Induced Obesity

Figure 4

(a) Expression of the lipogenic gene Fasn and the insulin sensitivity genes Glut4 and Irs1 were not significantly altered in WAT from KO mice. (b) Compared to WAT from WT mice on HFD, miR-155 KO WAT had reduced Cd11b and Ccl2, suggesting that miR-155 deletion dampened obesity-related inflammatory responses. * indicates p < 0.05.

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