Table 3 Kinetic parameters of SaThiM phosphorylating THZ12, cpd 1 and cpd 2.

From: Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus – Insights into a novel pro-drug approach addressing MRSA infections

 

Specific Activity [nmol/min/mg]

KM [μM]

kcat [min−1]

THZ12

4880 ± 488

44 ± 5

137 ± 13

cpd 1

7297 ± 267

834 ± 147

215 ± 8

cpd 2

7418 ± 91

831 ± 169

218 ± 3

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