Figure 3: Comparison of the methylation profiles of adenine and cytosine residues between the 2T and 156T strains.

Only positions with p-values lower than 10−4 (score ≤ 40) and larger than 25 (coverage > 25) were selected as modified bases. The locations of methylated adenines within GTCGAm6AC (a), GTATAm6AC (b) and GTCTAm6AC (c) and of methylated cytosine, m4C (d), are displayed in the 2 T (left panel) and 156 T genomes (right panel) as bars. The length of each bar represents the level of confidence in the methylation (−10*log[P-value]). Methylations in the + and − strands are indicated by red and blue bars, respectively. In the outermost circles, the locations dividing the genome into 6 equal parts are indicated as ticks.