Table 1 Baseline characteristics of HCV patients.

From: Elevated on-treatment levels of serum IFN-gamma is associated with treatment failure of peginterferon plus ribavirin therapy for chronic hepatitis C

 

SVR

Non-SVR

p-vale

n

73

19

 

Sex (male, %)

41(56.2%)

8(42.1%)

0.274

Age (mean ± SD)

52.0 ± 8.3

51.7 ± 13.1

0.919

GOT(IU/L) (mean ± SD)

99.5 ± 57.8

90.6 ± 60.1

0.553

GPT(IU/L) (mean ± SD)

164.5 ± 107.1

119.3 ± 71.3

0.034

Fibrosis

 0–2

53(74.6%)

14(73.7%)

0.932

 3–4

18(25.4%)

5 (26.3%)

 

Viral load

 high (>4 × 105 IU/ml)

25 (34.2%)

12 (66.7%)

0.012

 Low (≦4 × 105 IU/ml)

48 (65.8%)

6 (33.3%)

 

HCV genotype

 1b

33(45.2%)

11(57.9%)

0.324

 Non-1b

40(54.8%)

8(42.1%)

 

IL28B_rs8099917

 TT

51(85.0%)

11(73.3%)

0.279

 GT

9(15.0%)

4(26.7%)

 
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