Table 2 The association between IFN-γ and sustained virologic response in HCV patients.

From: Elevated on-treatment levels of serum IFN-gamma is associated with treatment failure of peginterferon plus ribavirin therapy for chronic hepatitis C

IFN-γ (pg/ml)

SVR

>Non-SVR

X2 p-value

Multivariate p-value

p-value

(n = 73)

(n = 19)

OR (95% C.I)

IFN-γ 4wk

 <180

64(86.5%)

10(13.5%)

6.0 × 10−4

6.79 (1.91~24.09)

3.0 × 10−3

180

9(50.0%)

9(50.0%)

   

IFN-γ 12wk

 <120

53(89.8%)

6(10.2%)

9.0 × 10−4

11.55 (3.05~43.77)

3.2 × 10−4

120

20(60.6%)

13(39.4%)

   

IFN-γ EOT

 <40

52(89.7%)

6(10.3%)

1.4 × 10−3

4.93 (1.52~15.93)

7.7 × 10−3

40

21(61.8%)

13(38.2%)

   
  1. p.s. Adjusted for viral load and GPT. EOT: end of treatment.