Table 4 The association between IFN-γ and sustained virologic response in HCV subgroups (High vs. Low viral load).
IFN-γ (pg/ml) | Low viral load (≦4 × 105 IU/ml) | High viral load (>4 × 105 IU/ml) | Odds ratio | |||||
|---|---|---|---|---|---|---|---|---|
SVR | Non-SVR | X2 or Fisher’s | Odds ratio | SVR | Non-SVR | X2 or Fisher’s | ||
(n = 48) | (n = 6) | p-value | OR (95% C.I) | (n = 25) | (n = 12) | p-value | OR (95% C.I) | |
IFN-γ 4wk | ||||||||
<180 | 43(91.5%) | 4(8.5%) | 0.168 | 1.28 (0.80~2.06) | 21 (80.8%) | 5 (19.2%) | 0.018 | 2.22 (0.99~4.96) |
≧180 | 5(71.4%) | 2(28.6%) | 4 (36.4%) | 7 (63.6%) | ||||
IFN-γ 12wk | ||||||||
<120 | 37 (94.9%) | 2 (5.1%) | 0.044 | 1.29 (0.95~1.77) | 16 (84.2%) | 3 (15.8%) | 0.038 | 1.68 (1.02~2.78) |
≧120 | 11 (73.3%) | 4 (26.7%) | 9 (50.0%) | 9 (50.0%) | ||||
IFN-γ EOT | ||||||||
<40 | 37 (94.9%) | 2 (5.1%) | 0.044 | 1.29 (0.95~1.77) | 15 (78.9%) | 4 (21.1%) | 0.170 | 1.42 (0.89~2.28) |
≧40 | 11 (73.3%) | 4 (26.7%) | 10 (55.6%) | 8 (44.4%) | ||||
