Table 1 Relative organs weights (% of body weight) (experiments 1–3).

From: Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice

 

SD

HFD

HFD + Antibiotics

Sham

Castration

Sham

Castration

Sham

Castration

Visceral WAT

 Mesenteric

1.75 ± 0.10

1.62 ± 0.17

2.00 ± 0.22

2.73 ± 0.18*

2.24 ± 0.23

2.46 ± 0.30

 Perirenal/retroperitoneal

1.71 ± 0.15

1.75 ± 0.16

2.07 ± 0.16

2.88 ± 0.21*

2.64 ± 0.13

2.63 ± 0.21

 Epididymal

3.73 ± 0.37

3.31 ± 0.72

4.65 ± 0.30

4.62 ± 0.47

4.78 ± 0.35

5.58 ± 0.74

Subcutaneous WAT

 Inguinal

2.50 ± 0.21

3.31 ± 0.28*

4.91 ± 0.27

7.87 ± 0.46*

3.95 ± 0.21

5.55 ± 0.41*

Skeletal muscle

 Quadriceps

1.00 ± 0.04

1.03 ± 0.06

0.85 ± 0.04

0.69 ± 0.04*

1.18 ± 0.03

1.11 ± 0.09

 Hamstrings

2.09 ± 0.04

2.13 ± 0.06

1.93 ± 0.04

1.60 ± 0.04*

2.31 ± 0.08

2.10 ± 0.20

 BC/LA

0.26 ± 0.01

0.04 ± 0.003*

0.23 ± 0.009

0.02 ± 0.002*

0.27 ± 0.01

0.03 ± 0.004*

Others

 Liver

4.19 ± 0.16

3.80 ± 0.12

4.15 ± 0.26

4.00 ± 0.23

3.64 ± 0.07

3.75 ± 0.49

 Kidney

1.30 ± 0.05

0.99 ± 0.03*

1.30 ± 0.10

0.85 ± 0.03*

1.33 ± 0.04

0.91 ± 0.03*

 Pancreas

0.83 ± 0.02

0.89 ± 0.09

0.88 ± 0.08

0.74 ± 0.06

0.77 ± 0.03

0.79 ± 0.04

 Heart

0.41 ± 0.01

0.37 ± 0.01*

0.37 ± 0.01

0.32 ± 0.01*

0.35 ± 0.01

0.30 ± 0.01*

  1. Data are expressed as means ± SEM. Statistical differences (*p < 0.05) were determined between sham-operated mice and castrated mice.