Figure 1

Survival Functions.

Kaplan-Meier survival analysis for 242 critically ill cirrhotic patients according to the 3 AKI classifications on the first day of ICU admission. (a) Based on the KDIGO classification, the 180-day cumulative survival rates differed significantly for patients without AKI versus patients with KDIGO stages 1 to 3 (p < 0.001). The comparisons between patients with KDIGO stage 1 and those with KDIGO stages 2 to 3 and between patients with KDIGO stages 2 and those with KDIGO stage 3 have been depicted on the figure. (b) Based on the AKIN classification, the 180-day cumulative survival rates differed significantly for patients without AKI versus patients with AKIN stages 1 to 3, p < 0.001). The comparisons between patients with AKIN stage 1 and those with AKIN stages 2 to 3 and between patients with AKIN stages 2 and those with AKIN stage 3 have been depicted on the figure. (c) Based on the RIFLE classification, the 180-day cumulative survival rates differed significantly for patient without AKI versus patients with RIFLE-R, RIFLE-I and RIFLE-F (p < 0.001). The comparisons between patients with RIFLE-R and those with RIFLE-I to F and between patients with RIFLE-I and those with RIFLE-F have been depicted on the figure. (d) Patients with AKI diagnosed according to KDIGO but missed by AKIN or RIFLE classification had significantly lower hospital survival rate than patients without AKI (Log Rank P < 0.001). (e) Patients with AKI diagnosed according to KDIGO but missed by AKIN or RIFLE classification had significantly lower 180-day cumulative survival rate than patients without AKI (Log Rank P = 0.001). * Abbreviation: AKI, acute kidney injury; RIFLE, risk of renal failure, injury to kidney, failure of kidney function, loss of kidney function and end-stage renal failure; AKIN, acute kidney injury network; KDIGO, kidney disease improving global outcomes.