Table 2 Patients’ demographic data and clinical characteristics.

From: Acute Kidney Injury Classification for Critically Ill Cirrhotic Patients: A Comparison of the KDIGO, AKIN and RIFLE Classifications

 

All patients (n = 242)

Survivors (n = 90)

Non-survivors (n = 152)

p-value

Age (years)

58 ± 14

58 ± 14

58 ± 14

NS (0.775)

Gender (M/F)

183/59

72/18

111/41

NS (0.278)

Body weight (kg)

65.2 ± 12.7

65.3 ± 12.6

65.1 ± 12.8

NS (0.919)

Length of ICU stay (days)

8 ± 8

6 ± 6

9 ± 9

0.002

Length of hospital stay (days)

26 ± 24

29 ± 28

24 ± 22

NS (0.093)

MAP, ICU admission (mmHg)

72.3 ± 15.6

78.8 ± 14

68 ± 15

<0.001

Glasgow coma scale, ICU admission

9 ± 5

11 ± 5

8 ± 5

<0.001

Serum Creatinine, ICU first day (mg/dl)

2.6 ± 2.1

1.6 ± 1.3

3.2 ± 2.1

<0.001

Leukocytes, ICU first day (10^3/dl)

13.0 ± 7.9

10.8 ± 6.3

14.4 ± 8.5

<0.001

Hemoglobin, ICU first day (g/dl)

9.1 ± 2.1

9.1 ± 2.0

9.1 ± 2.2

NS (0.940)

Platelets, ICU first day (x10^9/l)

95 ± 74

90 ± 55

98 ± 83

NS (0.422)

Albumin, ICU first day (g/dl)

2.5 ± 0.6

2.6 ± 0.6

2.4 ± 0.5

<0.001

Sodium, ICU first day (mmol/l)

137 ± 10

138 ± 8

137 ± 10

NS (0.292)

Bilirubin, ICU first day (mg/dl)

10.2 ± 11.1

4.7 ± 6.5

13.9 ± 11.9

<0.001

Prothrombin time INR, ICU first day

2.3 ± 1.5

1.7 ± 0.5

2.7 ± 1.8

<0.001

AST, ICU first day

179 ± 501

95 ± 176

228 ± 613

0.021

ALT, ICU first day (units/l)

518 ± 1962

212 ± 412

704 ± 2450

0.013

DM (yes/no)

72/170

32/58

40/112

NS (0.147)

Hepatic encephalopathy (yes/no)

151/91

47/43

104/48

0.014

Previous ascites (yes/no)

186/56

68/22

118/34

NS (0.753)

Previous SBP (yes/no)

53/189

13/77

40/112

0.036

Previous EV bleeding (yes/no)

134/108

58/32

76/76

0.033

Previous peptic ulcer bleeding (yes/no)

85/157

29/61

56/96

NS (0.489)

Previous hepatoma (yes/no)

74/168

27/63

47/105

NS (1.000)

Previous renal failure (yes/no)

63/179

18/72

45/107

NS (0.129)

Respiratory failure, ICU first day (yes/no)

151/91

49/41

102/50

NS (0.055)

Sepsis, ICU admission (yes/no)

116/71

32/24

84/47

NS (0.412)

Child-Pugh points

11 ± 2

10 ± 2

12 ± 2

<0.001

MELD score

28 ± 12

19 ± 7

33 ± 10

<0.001

APACHE II

25 ± 9

20 ± 7

28 ± 9

<0.001

APACHE III

105 ± 40

78 ± 31

121 ± 35

<0.001

SOFA

11 ± 5

7 ± 3

13 ± 4

<0.001

  1. Abbreviation: M, male; F, female; ICU, intensive care unit; MAP, mean arterial pressure; INR, international normalized ratio; AST, aspartate aminotransferase; ALT, alanine aminotransferase; DM, diabetes mellitus; SBP, spontaneous bacterial peritonitis; EV, esophageal varices; MELD, model for end-stage liver disease; APACHE, acute physiology and chronic health evaluation; SOFA, sequential organfailure assessment.
  2. Values in bold are statistically significant (P-value < 0.05).
  3. There were significant differences in length of ICU stay, mean arterial pressure, Glasgow coma scale, serum creatinine, albumin, bilirubin, AST, ALT, prothrombin time INR, leukocyte count, presence of hepatic encephalopathy, previous SBP, previous EV bleeding, liver and ICU prognostic scores.
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