Table 3 Causes of cirrhosis and reasons of ICU admission according to hospital survival.

From: Acute Kidney Injury Classification for Critically Ill Cirrhotic Patients: A Comparison of the KDIGO, AKIN and RIFLE Classifications

 

All patients (n = 242)

Survivors (n = 90)

Non-survivors (n = 152)

p-value

Causes of cirrhosis

 Alcoholic

54 (22.3%)

24 (26.7%)

30 (19.7%)

NS (0.263)

 Hepatitis B

65 (26.9%)

19 (21.1%)

46 (30.3%)

NS (0.135)

 Hepatitis C

52 (21.5%)

21 (23.3%)

31 (20.4%)

NS (0.629)

 Alcoholic + Hepatitis B

30 (12.4%)

8 (8.9%)

22 (14.5%)

NS (0.231)

 Alcoholic + Hepatitis C

7 (2.9%)

4 (4.4%)

3 (2.0%)

NS (0.429)

 Hepatitis B + Hepatitis C

0 (0%)

0 (0%)

0 (0%)

–

 Alcoholic + Hepatitis B + Hepatitis C

6 (2.5%)

1 (1.1%)

5 (3.3%)

NS (0.416)

 Other causesa

28 (11.6%)

13 (14.4%)

15 (9.9%)

NS (0.303)

Primary ICU admission

 Severe UGI bleeding

92 (38.0%)

46 (51.1%)

46(30.3%)

0.002

 Hepatic encephalopathy

60 (24.8%)

26 (28.9%)

34 (22.4%)

NS (0.283)

 Respiratory failure

28 (11.6%)

6 (6.7%)

22 (14.5%)

NS (0.095)

 Severe sepsis

47 (19.4%)

7 (7.8%)

40 (26.3%)

<0.001

 HCC rupture

10 (4.1%)

4 (4.4%)

6 (3.9%)

NS (1.000)

 Acute pancreatitis

2 (0.8%)

0 (0%)

2 (1.3%)

NS (0.531)

 Acute renal failure

6 (2.5%)

1 (1.1%)

5 (3.3%)

NS (0.416)

  1. Abbreviation: HCC, hepaocellular carcinoma; ICU, intensive care unit; UGI, upper gastrointestinal;
  2. a “Other causes” includes primary biliary cirrhosis, autoimmune hepatitis, andother unknown causes.
  3. Values in bold are statistically significant (P-value < 0.05).
  4. Cause of cirrhosis: none of the causes was independently associated with in-hospital mortality.
  5. Primary ICU admission reason: sever UGI bleeding and severe sepsis were independently associated with in-hospital mortality.
Back to article page