Table 1 Required sample sizes (N) per group in a group comparison design as a function of the number of fMRI volumes (influencing precision) and the expected size of the raw group difference in MSE.

From: On the estimation of brain signal entropy from sparse neuroimaging data

  

Amount of Data

Scale

MSE Precision

Estimated group-wise N required to achieve a specific raw group difference in MSE of:

0.05

0.10

0.15

Statistical Power (1− β )

0.80

10 × 16

1

0.09

51

13

6

 

5

1.80

>1000

>1000

>1000

10 × 32

1

0.08

41

11

5

 

5

0.55

>1000

474

211

10 × 64

1

0.07

31

8

4

 

5

0.25

392

98

44

885

1

0.06

23

6

3

 

5

0.10

63

16

7

0.90

10 × 16

1

0.09

68

17

8

 

5

1.80

>1000

>1000

>1000

10 × 32

1

0.08

54

14

6

 

5

0.55

>1000

635

282

10 × 64

1

0.07

42

11

5

 

5

0.25

525

132

59

885

1

0.06

31

8

4

 

5

0.10

84

21

10

0.95

10 × 16

1

0.09

85

22

10

 

5

1.80

>1000

>1000

>1000

10 × 32

1

0.08

67

17

8

 

5

0.55

>1000

785

349

10 × 64

1

0.07

51

13

6

 

5

0.25

649

163

73

885

1

0.06

38

10

5

 

5

0.10

104

26

12

  1. Note. Precision is defined as the SD of MSE values and can therefore directly be used to approximate the effect size of the expected effect in the statistical power calculation. Precision values shown here are the 95th percentiles of the precision value distributions across voxels, thus providing a rather conservative estimation of required sample sizes.