Figure 2: Cell viability in cells treated with AHC compounds. | Scientific Reports

Figure 2: Cell viability in cells treated with AHC compounds.

From: Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways

Figure 2

(a–d) Prostate cancer PC-3 cells were treated with varying concentrations of (a) 7-O-galloyl catechin, (b) catechin, (c) catechin gallate, or (d) methyl gallate for 24, 48 and 72 h as indicated. TBB was included as a positive control and DMSO was included as a negative control at a concentration equivalent to 100 μM AHC compound. Cell viability was determined relative to the untreated (0 μM) cells. (e,f) Breast cancer MDA-MB-231 cells were treated with varying concentrations of (e) catechin gallate, or (f) methyl gallate for 24 or 48 h, as indicated. All other conditions are as describe for (a–d). Data are presented as mean ± SEM (n = 3). Data analyzed by two-way ANOVA with Bonferroni post-test. The asterisks *, **, ***indicate significant difference at p < 0.05, p < 0.001 and p < 0.0001, respectively, from the untreated control cells.

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