Figure 7: Proposed signaling pathways and anti-apoptotic proteins expression affected by compounds isolated from A. hydaspica.

A diagram of the effects of AHC compounds, in PC-3 and MDA-MB-231 cells as detected by western blot analyses is depicted. Effective compounds against PC-3 cells are depicted in grey boxes. Effective compounds against MDA-MB-231 cells are depicted in red boxes. Arrows indicate activation or stimulation. Blocked lines indicate inhibition. Yellow circles indicate phosphorylation.