Figure 5
From: Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer
Transgene expression following in vivo minicircle and plasmid DNA transfections.
Luciferase activity at 1, 7 and 14 days following a single dose of LED-1 complexes containing pMC.Luc2 plasmid DNA or MC.Luc2 minicircle DNA at either equimolar or equal mass quantities delivered by oropharyngeal instillation of CD1 mice. NS, not significant; *P < 0.05; **P < 0.01; Kruskal-Wallis test followed by Dunn’s post-test analysis to assess significance. Values are background subtracted and bar represents median RLU/mg.
