Figure 5: GPE inhibits the clonogenicity of human PCa cells under normoxic and hypoxic conditions. | Scientific Reports

Figure 5: GPE inhibits the clonogenicity of human PCa cells under normoxic and hypoxic conditions.

From: Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity

Figure 5

(A,B) Human PCa 22Rv1 and PC3 cells (~1 × 103 cells per well) were cultured in 6-well plates and treated with GPE (1–5 μg/ml) under normoxic (21% O2) or hypoxic (1% O2) conditions for 48 hrs. Thereafter, cells were maintained under normoxic conditions and clones were counted after 7 days. Each value represents mean ± SEM of three samples for each treatment. #p ≤ 0.01; *p ≤ 0.001.

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