Figure 4: Global gene expression analysis of single blastocysts following microarray. | Scientific Reports

Figure 4: Global gene expression analysis of single blastocysts following microarray.

From: Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

Figure 4

(a) PCA of microarray data from single blastocysts. Red, blue and brown points represent individual transcriptomes from ICSI BCB+ , ICSI BCB− and mICSI BCB− blastocysts, respectively. (b) Heat map of global gene expression following Pearson’s correlation to determine hierarchical clustering between blastocysts of each group. (c) Venn diagram representing differentially expressed genes between ICSI BCB+ and ICSI BCB−; mICSI BCB− and ICSI BCB−; and mICSI BCB− and ICSI BCB+ blastocysts following unpaired t-tests, with FC > 2 (abs) and significance of p < 0.01.

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