Table 2 MtDNA copy number in MII oocytes and 2-cell and blastocyst stage embryos.

From: Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

Oocyte selection and fertilisation

mtDNA copy number ± SEM

Ratio

MII

2 cells

Blastocyst

2 cells/MII

Blastocyst/MII

BCB+ IVF

147063 ± 25325a

91630 ± 19950a,b

244245 ± 28765

62.3%

166.1%

BCB+ ICSI

147063 ± 25325a

40926 ± 10057a

263067 ± 45966

27.8%

178.9%

BCB ICSI

44749 ± 10574b

22419 ± 7588a

265000 ± 33329

50.1%

592.2%

BCB+ mICSI

147063 ± 25325a

nd

273712 ± 52787

nd

186.1%

BCB mICSI

44749 ± 10574b

198539 ± 69880a

214841 ± 49107

443.7%

480.1%

  1. ANOVA between BCB+ and BCB for IVF, ICSI and mICSI inseminations with different superscripts representing significant differences, p < 0.05.