Figure 3
From: Micheliolide inhibits LPS-induced inflammatory response and protects mice from LPS challenge
MCL inhibits the production of LPS-induced proinflammatory cytokines, chemokines, type I interferon and anti-inflammatory cytokines in mouse peritoneal macrophages.
Mouse peritoneal macrophages (3.5 × 105/300 μL) were generated as indicated and stimulated by MCL with or without LPS (100 ng/mL) for 6 h or 18 h. The concentrations of IL-6 (a), TNF-α (b), MCP-1 (c), IFN-β (d) and IL-10 (e) in the supernatants were measured by ELISA. Data are shown as mean ± SD of three independent experiments; *p < 0.05.
