Figure 1 | Scientific Reports

Figure 1

From: Hypoxia-induced sensitisation of TRPA1 in painful dysesthesia evoked by transient hindlimb ischemia/reperfusion in mice

Figure 1

Changes in hindpaw blood flow induced by transient hindlimb ischemia/reperfusion.

To induce transient hindlimb ischemia in mice, the left hindlimb just proximal to the ankle joint was compressed by ligation with a string for 60 min. The ligature was rapidly removed for reperfusion. (a) Representative photographs (upper panels) and blood flow images (lower panels) of the hindpaws of a mouse before and during ischemia and just after reperfusion. (b) The blood flow in the ipsilateral hindpaw was normalised to that in the contralateral hindpaw and the value obtained just before ischemia served as 100%. Data are presented as means of the percentage ± S.E.M. n = 3.

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