Figure 3 | Scientific Reports

Figure 3

From: Hypoxia-induced sensitisation of TRPA1 in painful dysesthesia evoked by transient hindlimb ischemia/reperfusion in mice

Figure 3

Spontaneous licking following transient hindlimb ischemia/reperfusion.

Time course of spontaneous licking after reperfusion following a transient hindlimb ischemia for 15, 30 and 60 min. (a) The time spent licking the ipsilateral hindpaw was measured every 1 min for 20 min after reperfusion following 60-min hindlimb ischemia (n = 7) or sham treatment (n = 6). *P < 0.05, **P < 0.01, ***P < 0.001 vs sham treatment. (b,c) The time spent licking the ipsilateral hindpaw every 5 min for 40 min (b) and total time spent licking for 40 min (c) was measured after reperfusion following 15, 30 or 60-min hindlimb ischemia/reperfusion or sham treatment. n = 4–15, **P < 0.01, ***P < 0.001 vs sham treatment.

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