Table 1 IC50 values of multiple drugs in HCC cells treated with doxorubicin (0.2 μg/mL) (Pre-Dox), hypoxia (1% O2), ionizing radiation (10 Gy) (Pre-IR), compared with control groups (normality) (n = 6).

From: Regulation of Multi-drug Resistance in hepatocellular carcinoma cells is TRPC6/Calcium Dependent

Cell lines

Drugs

Stimuli

Normality

Hypoxia

Pre-Dox

Pre-IR

 

Doxorubicin (μg/mL)

0.2026

1.062 *

2.900 *

1.130 *

Huh7

5-Fluorouracil (mg/mL)

0.03799

0.2278 *

3.106 *

0.1739 *

 

Cisplatin (μg/mL)

2.831

5.841 *

11.34 *

5.054 *

 

Doxorubicin (μg/mL)

0.2776

0.5824 *

1.311 *

0.7392 *

HepG2

5-Fluorouracil (mg/mL)

0.02016

0.05581 *

1.282 *

0.06292 *

 

Cisplatin (μg/mL)

3.288

6.630 *

13.11 *

5.937 *

  1. Statistical significances were assessed using Student’s T-Test.
  2. *p < 0.05, stimuli groups compared with control groups (normality).
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