Figure 2 | Scientific Reports

Figure 2

From: Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks

Figure 2

(A) Effect of a 24-h treatment with DMSO, SFOM-0046 (6 μM) or cisplatin (15 μM) on the cell cycle progression of M21, HT29, HT-1080 and HeLa cells. (B) Effect of DMSO, SFOM-0046 (6 μM) and cisplatin (30 μM) on the phosphorylation of H2AX into γ-H2AX after 24 h of treatment in M21 and HT29 cells. (C) Quantification of the number of M21 cells displaying less and more than 10 γ-H2AX foci.

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