Figure 4 | Scientific Reports

Figure 4

From: Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks

Figure 4

Effect of DMSO and SFOM-0046 at 1.5 and 3 μM on the phosphorylation of 53BP1 and DNA-PKcs after 24 h of treatment on: (A) M21 and (B) HT29 cells. Quantification of the number of : (C) M21 and (D) HT29 cells displaying less than 10, 10–40 and over 40 53BP1 foci. Quantification of the number of: (E) M21 and (F) HT29 cells displaying less than 10, 10–40 and over 40 DNA-PK foci.

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