Figure 6 | Scientific Reports

Figure 6

From: Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks

Figure 6

Cells viability of (A) HT29 and M21 as well as (B) HCT116 (p53+/+ and p53−/−) cells treated with escalating concentrations of SFOM-0046. (C) Effect of DMSO and SFOM-0046 on the p53 expression level of HT29 and M21 cells at different treatment times. (D) Confirmation of the p53 (p en minuscule) status of the isogenic HCT116 p53+/+ and HCT116 p53−/− cells.

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