Figure 6 | Scientific Reports

Figure 6

From: Genome-wide Long Non-coding RNA Analysis Identified Circulating LncRNAs as Novel Non-invasive Diagnostic Biomarkers for Gynecological Disease

Figure 6

Graphical view of lncRNA-miRNA-mRNA network for lncRNAs.

(A) Cluster analysis of the expression data of target genes using the GG-H array. Cluster analysis of lncRNA expression in endometriosis patient serum and serum controls, eutopic endometrium (EU) tissue sample, ectopic endometrium (EC) tissue sample and healthy tissue control (C). The 68 target genes are displayed. The expression values are represented in yellow and blue to show expression above and below the median expression value across all samples, respectively. (B) Graphical view of lncRNA-miRNA-mRNA network for 7 candidate lncRNAs. Boxes correspond to lncRNAs, diamonds correspond to miRNAs, circles correspond to mRNAs and the edges correspond to direct interaction links. The most significant regions are marked with background colors and the labels describe the main functions assigned.

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