Figure 3 | Scientific Reports

Figure 3

From: Deletion of Galectin-3 Enhances Xenobiotic Induced Murine Primary Biliary Cholangitis by Facilitating Apoptosis of BECs and Release of Autoantigens

Figure 3

Gal-3 deletion leads to increase of CD8+ T lymphocytes and inflammatory phenotype of DCs in liver infiltrates after PBC induction.

(A) Representative dot plots displaying the frequency and (B) total numbers of CD4+ and CD8+ T lymphocytes calculated per liver. (C) Total numbers of CD11c+ DCs in the livers. (D) Expression of markers of activation on CD11c+ gated cells. (E) Total numbers of DCs expressing CD86 and MHC II. Representative dot plots (F,G) total numbers of DCs expressing TNF-alpha. Data are presented as the mean+SE, 9 mice per group, **p < 0.005; *p < 0.05.

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