Table 3 Univariate logistic regression model to assess risk alleles in individuals with thalidomide embryopathy and in individuals of the unaffected group.

From: New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors

Risk Alleles of NOS3 Gene

Presence

Absence

Odds Ratio (95% IC)

P-Value

n

%

n

%

(−786)C + (VNTR)4b

91

53.8

78

46.2

2.570 (1,20–5,80)

0.018

(−786)C + (VNTR)4b + (894)T

68

52.6

101

36.6

1.921 (0,93–4,01)

0.079

  1. CI: confidence interval; Polymorphisms used in the model are rs2070744 (−786C), rs61722009 (VNTR) and rs1799983 (894T).
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