Table 1 Features of the receiver operating characteristic curve of miRNAs for diagnosing IgAN.

From: Selection of urinary sediment miRNAs as specific biomarkers of IgA nephropathy

 

AUC

95% CI

P Value

Optimal cut-off value

Sensitivity (%)

specificity (%)

miR-25-3p

0.884

0.831–0.937

<0.001

2-ΔΔct = 0.045

87.1

79.4

miR-144-3p

0.869

0.811–0.927

<0.001

2-ΔΔct = 0.006

82.3

77.5

miR-486-5p

0.935

0.897–0.973

<0.001

2-ΔΔct = 0.035

93.5

85.3

  1. AUC, the area under the ROC curve; CI, confidence interval. Normal control, n = 82; disease control, n = 40; IgAN group, n = 93.