Table 3 Basic characteristics of the included studies.

From: Probiotic supplementation does not improve eradication rate of Helicobacter pylori infection compared to placebo based on standard therapy: a meta-analysis

Author of study

Age (probiotics group)

Age (control group)*

M/F (probiotics group)

M/F (control group)*

Type of patients included

Nista et al.

46 ± 13

43 ± 13

33/27

22/38

Free of gastrointestinal symptoms

Navarro- Rodriguez et al.

50.4

48.4

21/34

19/33

51 PU patients and 56 dyspepsia patients

Cremonini et al.

–

–

–

–

Free of gastrointestinal symptoms

Cindoruk et al.

45.82 ± 13.35

47.56 ± 13.53

26/36

18/44

Dyspepsia patients

Manfredi et al.

46.4

50.6

39/34

37/39

Free of gastrointestinal symptoms

Shavakhi et al.

42.3 ± 13.3

42.2 ± 13.2

49/41

60/30

Patients with history of PU

Myllyluoma et al.

57.3

53.8

10/13

8/16

Free of gastrointestinal symptoms

Armuzzi et al.

–

–

–

–

Free of gastrointestinal symptoms

Ziemniak et al.

44.4 ± 13.3

43.7 ± 10.3

14/39

78/114

Patients with PU or gastritis

de Bortoli et al.

51.5±13.7

50.1 ± 15.2

56/49

54/47

Free or mild of gastrointestinal symptoms, among 25 PU patients

Sheu et al.

47.8

45.9

40/40

38/42

84 PU patients and 76 dyspepsia patients

Song et al.

49.76±11.7

49.84 ± 11.4

185/145

219/112

Patients with gastrointestinal symptoms, among 492 PU patients

Park et al.

45.2±19.8

47.6 ± 18.5

96/80

95/81

Patients with gastrointestinal symptoms, among 142 PU patients

Kim et al.

48.1 ± 12.4

53.7 ± 12.0

71/97

89/90

113 PU patients and 234 dyspepsia patients

Yasar et al.

38.32 ± 10.66

36.95 ± 8.62

11/27

14/24

Dyspepsia patients

Canducci et al.

–

–

–

–

Dyspepsia patients or patients with history of PU

Armuzzi et al.

–

–

–

–

Free of gastrointestinal symptoms

Medeiros et al.

50.7

53.8

18/13

14/17

Patients with history of PU

Scaccianoce et al.

50

48

7/8

6/10

Free of gastrointestinal symptoms

Deguchi et al.

55.9

57.8

76/39

68/46

Patients with history of PU

Imase et al.

–

–

–

–

Patients with history of PU

  1. *In this table, the control group contains groups with or without a placebo.
  2. **PU = peptic ulcer.