Figure 4
From: A non-human primate model of radiation-induced cachexia
Quantification of skeletal muscle mass using CT imaging.
(a) Demarcation of skeletal muscle tissues at the 3rd lumbar vertebra. The muscles in this area include the psoas major & minor muscle and erector spinae muscles. The region was shown by the pink color in three different views. (b) CT images of skeletal muscle at the 3rd lumbar vertebra in a NHP exposed to 10 Gy PBI/BM5 which was euthanized on d 30. (c) CT images of skeletal muscle at the 3rd lumbar vertebra in a NHP exposed to 10 Gy PBI/BM5 which was euthanized on d 164 after radiation exposure. (d) CT images of skeletal muscle at 3rd lumbar vertebra in a NHP exposed to 11 Gy PBI/BM5. This NHP survived the 180 d study after radiation exposure. A graph showing the time course of body weight and skeletal muscle change is included for each NHP. Blue line, body weight change; red line, skeletal muscle change.
