Figure 5
From: A non-human primate model of radiation-induced cachexia
Histological morphology of muscle tissue from five NHP exposed to 10 or 11 Gy PBI/BM5.
(a) Central nuclei: muscle nuclei (green arrows) are located inside rather than at the periphery of the muscle fibers; (b) Adipose replacement of muscle fibers. The hydrophobic fat-rich structures in adipocytes show a clear cytoplasm structure; (c) Polynuclei in muscle fibers (black arrows); (d) inflammatory cell (blue arrows) infiltration of muscle fibers; and (e) branched muscle fibers (left part of the muscle tissue). The table shows radiation doses, time of euthanasia and BW change at euthanasia compared to pre-irradiation BW for each of the five animals. Scale bar = 100 micron.
