Table 1 Association of all polymorphisms in TBX20 promoter region with CHDs in case-control studies.
db SNP No. | Genotype | Pattern | Case | Control | P value | OR (95% CI) | Hardy-Weinberg equilibrium* |
|---|---|---|---|---|---|---|---|
rs1003549 | Codominant | AA/AG/GG | 201/23/0 | 258/29/3 | |||
Dominant | AA/AG + GG | 201/23 | 258/32 | ||||
Recessive | AA + AG/GG | 224/0 | 287/3 | ||||
Overdominant | AA + GG/AG | 201/23 | 261/29 | ||||
Log additive | A/G | – | – | 0.54 | 0.85 (0.50–1.44) | 0.074 | |
rs10235849 tag SNP | Codominant | AA/AT/TT | 138/78/10 | 148/115/27 | |||
Dominant | AA/AT + TT | 138/88 | 148/142 | ||||
Recessive | AA + AT/TT | 216/10 | 263/27 | ||||
Overdominant | AA + TT/AT | 148/78 | 175/115 | ||||
Log additive | A/T | – | – | 0.0069 | 0.68 (0.51–0.90) | 0.57 | |
rs336284 | Codominant | TT/TC/CC | 73/113/37 | 76/139/76 | |||
Dominant | TT/TC + CC | 73/150 | 76/215 | ||||
Recessive | TT + TC/CC | 186/37 | 215/76 | ||||
Overdominant | TT + CC/TC | 110/113 | 152/139 | ||||
Log additive | T/C | – | – | 0.01 | 0.72 (0.56–0.93) | 0.48 |
