Figure 3: Performance evaluation.
From: Utilizing yeast chemogenomic profiles for the prediction of pharmacogenomic associations in humans
(A) Areas under the curves (AUC) obtained in a 10-fold cross-validation setting comparing our method (yeast based) to a similar human-based method, omitting the HIP/HOP score from feature construction. (B) AUC scores obtained for 140 joint valid associations in both our method and Hansen’s. (C) Performance evaluation on external data sources: A comparison of our predictions to different pathway categories downloaded from The Small Molecule Pathway Database (SMPDB). (D) A comparison of our prediction to different association types extracted from DrugBank.
