Table 3 Enriched categories in drugs with few PGx associations.
From: Utilizing yeast chemogenomic profiles for the prediction of pharmacogenomic associations in humans
Drug category | Hyper geometric p-value | # drugs |
---|---|---|
Histamine H1 Antagonists | 7.59E-09 | 22 |
Contrast Media | 9.21E-09 | 11 |
Diagnostic Agents | 4.98E-07 | 11 |
Anti-Inflammatory Agents, Non-Steroidal | 1.26E-06 | 21 |
Bisphosphonates | 8.06E-06 | 7 |
Muscle relaxant, Skeletal | 1.12E-05 | 8 |
Anti-Inflammatory Agents | 2.99E-05 | 24 |
Anti-Allergic Agents | 5.56E-05 | 13 |
Histamine Antagonists | 5.56E-05 | 13 |
Cyclooxygenase Inhibitors | 2.75E-04 | 10 |
Histamine H1 Antagonists, Non-Sedating | 1.19E-03 | 5 |
Antiresorptives | 1.25E-03 | 4 |
Muscle Relaxants, Genitourinary | 1.25E-03 | 4 |
Neuromuscular Nondepolarizing Agents | 1.25E-03 | 4 |
Bronchodilator Agents | 1.52E-03 | 10 |
Oxytocics | 3.51E-03 | 5 |
Antihypocalcemic Agents | 4.84E-03 | 7 |
Nicotinic Antagonists | 5.33E-03 | 4 |
Anti-Incontinence Agents | 6.69E-03 | 3 |
Cyclooxygenase 2 Inhibitors | 6.69E-03 | 3 |
Bone Density Conservation Agents | 7.35E-03 | 8 |
Muscle Relaxants, Central | 8.51E-03 | 6 |
Indicators and Reagents | 2.30E-02 | 3 |
Insecticides | 2.30E-02 | 3 |
Neuromuscular Agents | 2.71E-02 | 4 |
Carbonic Anhydrase Inhibitors | 3.56E-02 | 2 |
Expectorants | 3.56E-02 | 2 |
Hormone Replacement Agents | 3.56E-02 | 2 |
Leukotriene Antagonists | 3.56E-02 | 2 |
Muscle Relaxants, Respiratory | 3.56E-02 | 2 |
Phosphodiesterase 5 Inhibitors | 3.56E-02 | 2 |
Adrenergic alpha-1 Receptor Antagonists | 4.63E-02 | 4 |
Anti-Asthmatic Agents | 4.95E-02 | 3 |