Figure 4 | Scientific Reports

Figure 4

From: Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell

Figure 4

NMR analysis of the gankyrin-cjoc42 interaction.

(a) Changes in cross-peak intensity of the amide backbone of gankyrin in the presence of cjoc42. (b) Changes in chemical shifts of the amide backbone of gankyrin in the presence of cjoc42. (c) Residues 16, 38, 107, 108, 117, 169, 170, 183, with chemical shift changes (Δδ (15N-1H)) of >0.01 that also show significant intensity changes in the presence of cjoc42, are shown on the gankyrin structure.

Back to article page