Figure 1 | Scientific Reports

Figure 1

From: Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition

Figure 1

Overall structure of human dipeptidyl peptidase III.

(a) Cartoon representation of the structure of the unbound hDPP III. The upper lobe is shown in orange, the lower lobe in grey and the five-stranded β-core in deep teal. The catalytic zinc ion is depicted as a magenta sphere. (b) Cartoon representation of the closed conformation of hDPP III. The bound peptide is shown in red. The figure was prepared using the program PyMol (http://www.pymol.org/).

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