Figure 7: Effect of IL-17 on RPE cells. | Scientific Reports

Figure 7: Effect of IL-17 on RPE cells.

From: Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells

Figure 7

(A) Change in gene expression following apical IL-17 exposure (5 ng/mL) was measured in mature ARPE-19 cell monolayers. C3 as well as IL-17 expression levels demonstrated an increase in fold change over the control, whereas VEGF and CFH were unaltered. (B) Transepithelial resistance measurements indicated a loss in barrier function in response to apical application of 5 ng/mL IL-17 after four hours. Data shown are average values (±SEM) (n = 3).

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