Figure 1 | Scientific Reports

Figure 1

From: Significance of alpha smooth muscle actin expression in traumatic painful neuromas: a pilot study in rats

Figure 1

Increased level of α-SMA in the neuromas in the autotomy group.

(A) Immunohistochemistry analysis of α-SMA expression in the two groups at 4 weeks after transection (original magnification × 400). In the no-autotomy group, only slightly positive expression of α-SMA was seen; while in the autotomy group, extensively positive expression of α-SMA was present. The curved arrow shows the highly stained blood vessels and the straight arrow shows one of the positively stained myofibroblasts. (B) Protein expressions of α-SMA in the neuromas. GAPDH was used as the loading control and for band density normalization. (C) The optical density analysis of α-SMA proteins. Values are expressed as the mean ± SEM, n = 6 per group. *P < 0.05 versus the no-autotomy group.

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