Table 2 Thrombin inhibition activity of the compounds in DQP.
Compounds | Chemical family | Inhibition (%) a | IC50 (μM) |
|---|---|---|---|
Tanshinol | SA | 4.13 ± 1.19 | ND b |
Protocatechuic aldehyde | SA | −1.49 ± 3.18 | ND b |
Rosmarinic acid | SA | −1.70 ± 0.54 | ND b |
Lithospermic acid | SA | −0.89 ± 0.83 | ND b |
Salvianolic acid B | SA | −0.91 ± 0.00 | ND b |
Salvianolic acid A | SA | −0.82 ± 1.88 | ND b |
Ginsenoside-Rg1 | GS | −6.73 ± 1.01 c | ND b |
Ginsenoside-Rh1 | GS | −9.24 ± 1.99 c | ND b |
Ginsenoside-Rd | GS | −11.64 ± 2.97 c | ND b |
Ginsenoside-Rb1 | GS | −13.70 ± 3.71 c | ND b |
Dihydrotanshinone I | TN | 63.71 ± 3.13 | 92 ± 5 |
Cryptotanshinone | TN | 56.01 ± 2.21 | 102 ± 4 |
Tanshinone I | TN | 39.79 ± 0.40 | 333 ± 28 |
Tanshinone IIA | TN | 84.12 ± 1.81 | 39 ± 1 |
Argatroban | Positive control | 99.46 ± 0.33 | 17 ± 1 d |
