Table 2 Univariate and multivariate Cox proportional hazards regression analysis for OS.
Parameters | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age (years) | 0.125 | |||
≤60 | Reference | |||
>60 | 0.680(0.416–1.112) | |||
Gender | 0.547 | |||
Male | Reference | |||
Female | 0.859(0.524–1.409) | |||
Presentation | 0.419 | |||
Incidental | Reference | |||
Symptomatic | 0.832(0.533–1.300) | |||
Nephrectomy | 0.953 | |||
Radical | Reference | |||
Partial | 1.028(0.412–2.569) | |||
Tumor site | 0.072 | |||
Left | Reference | |||
Right | 1.510(0.964–2.367) | |||
Tumor size (cm) | 0.045 | 0.805 | ||
≤7 | Reference | Reference | ||
>7 | 1.614(1.012–2.574) | 1.070(0.626–1.828) | ||
T stage | <0.001 | <0.001 | ||
T1 + T2 | Reference | Reference | ||
T3 + T4 | 3.088(1.812–5.264) | 3.392(1.885–6.103) | ||
N stage | 0.028 | 0.603 | ||
N0 | Reference | Reference | ||
N1 | 1.820(1.068–3.103) | 1.200(0.604–2.385) | ||
M stage | <0.001 | <0.001 | ||
M0 | Reference | Reference | ||
M1 | 4.282(2.562–7.158) | 4.173(2.256–7.719) | ||
Histology | 0.021 | 0.060 | ||
Clear Cell | Reference | Reference | ||
Non-clear Cell | 1.875(1.099–3.201) | 1.926(0.973–3.812) | ||
Tumor necrosis | 0.012 | 0.028 | ||
Absent | Reference | Reference | ||
Present | 1.821(1.144–2.900) | 1.811(1.066–3.077) | ||
Microvascular invasion | 0.084 | |||
Absent | Reference | |||
Present | 1.709(0.931–3.139) | |||
Percentage sarcomatoid (%) | 0.035 | 0.003 | ||
<50 | Reference | Reference | ||
≥50 | 1.615(1.033–2.525) | 2.244(1.311–3.842) | ||
NLR | <0.001 | 0.006 | ||
<4.10 | Reference | Reference | ||
≥4.10 | 3.259(1.962–5.412) | 4.067(1.504–10.995) | ||
dNLR | 0.008 | 0.283 | ||
<2.57 | Reference | Reference | ||
≥2.57 | 1.926(1.189–3.120) | 0.613(0.251–1.498) | ||
PLR | <0.001 | 0.627 | ||
<132 | Reference | Reference | ||
≥132 | 2.386(1.482–3.840) | 1.172(0.618–2.220) | ||
LMR | 0.009 | 0.588 | ||
<3.11 | Reference | Reference | ||
≥3.11 | 0.547(0.348–0.859) | 0.850(0.472–1.531) | ||
