Figure 2 | Scientific Reports

Figure 2

From: Vancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils

Figure 2

Vancomycin reduced DNA damage and cell death of colon epithelial cells.

(A) Immunohistochemical analysis of distal colon at day 67. The DNA damage marker p-H2AX is shown. Scale bar: 50 μm. (B) Statistical analysis of p-H2AX positive cells in each field (×400). Data represent mean ± SEM (n = 4). ***p < 0.001. (C) Western blotting analysis of whole distal colon at day 67. The original blots are presented in Supplementary Fig. S7. AOM, azoxymethane; DSS, dextran sodium sulfate; N, neomycin; SEM, standard error of the mean; V, vancomycin; V/N, vancomycin and neomycin.

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