Figure 3 | Scientific Reports

Figure 3

From: Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling

Figure 3

Quercetin diminishes macrophage accumulation and inflammatory cytokines expression in the UUO kidneys.

(A) Representative micrographs showing the immuno-staining for F4/80 among different groups as indicated. Slides were co-stained with Abs against F4/80 and Laminin. Kidney sections were stained with DAPI to visualize the cell nuclei. Scale bar = 50 μm. (B) Graphic presentation showing F4/80 positive macrophage accumulation in the kidneys from various groups. *P < 0.05 compared with contra lateral kidneys (n = 7); #P < 0.05 compared with UUO kidneys with vehicle treatment (n = 7). (C) Graphic presentation showing the real-time PCR analysis results for TNFα, MCP1 and RANTES in the kidney tissue among groups. *P < 0.05 compared with contra lateral kidneys (n = 5); #P < 0.05 compared with UUO kidneys with vehicle treatment (n = 5).

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