Table 1 The genotypes distribution of rs2057178 and rs4331426 between tuberculosis cases and controls.
From: A rare variant at 11p13 is associated with tuberculosis susceptibility in the Han Chinese population
Genotypes | Controls (N = 763) n(%) | Cases (N = 763) n(%) | Crude ORs and 95% CI | Adjusted ORs and 95% CI* |
|---|---|---|---|---|
rs2057178 | ||||
CC | 692 (90.7%) | 724 (94.9%) | 1.00 | 1.00 |
CT | 67 (8.8%) | 37 (4.8%) | 0.53 (0.35–0.80) | 0.52 (0.34–0.78) |
TT | 4 (0.5%) | 2 (0.3%) | 0.48 (0.09–2.62) | 0.56 (0.10–3.10) |
Dominant model CT + TT vs. CC | 71 (9.4%) | 39 (5.1%) | 0.53 (0.35–0.79) | 0.52 (0.35–0.78) |
T allele frequency | 0.048 | 0.027 | χ2 = 14.07, P = 0.0002 | |
Hardy-Weinberg equilibrium | χ2 = 2.79, P = 0.095 | |||
rs4331426 | ||||
AA | 718 (94.1%) | 715 (93.7%) | 1.00 | 1.00 |
AG | 44 (5.8%) | 48 (6.3%) | 1.10 (0.72–1.67) | 1.08 (0.71–1.66) |
GG | 1 (0.1%) | 0 | NA | NA |
Dominant model AG + GG vs. AA | 45 (5.9%) | 48 (6.3%) | 1.07 (0.70–1.63) | 1.06 (0.70–1.62) |
G allele frequency | 0.030 | 0.031 | χ2 = 0.04, P = 0.8390 | |
Hardy-Weinberg equilibrium | χ2 = 0.142, P = 0.704 | |||
