Figure 1 | Scientific Reports

Figure 1

From: Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling

Figure 1

The pCAG-eGFP transgenic mice were generated by pronuclear microinjection.

(A) The structure of the pCAG-eGFP transgene. (B) Live imaging of the EGFP fluorescence in Akr1A1eGFP/+ and WT mice. (C) The in vivo EGFP fluorescence imaging of nine organs in the male and female Akr1A1eGFP/eGFP and Akr1A1eGFP/+ mice. Br: brain, He: heart, Lu: lung, Li: liver, Ke: kidney, Sp: spleen, Ov: ovary, Ut: uterus and Te: testis. (D) The chromosome FISH of the sexually dimorphic EGFP-expressing mouse line. The arrowhead shows the transgenic signals in the chromosome.

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