Figure 2: Adh deficiency significantly reduces PAM apoptosis and cytokine release. | Scientific Reports

Figure 2: Adh deficiency significantly reduces PAM apoptosis and cytokine release.

From: Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release

Figure 2

(A) The adhesion of A. pleuropneumoniae 5b WT, 5b ΔAdh and E. coli to PAMs; (B) The detection of LDH released by PAMs; (C) Cytokine array of A. pleuropneumoniae 5b WT- and 5b ΔAdh-infected PAMs; Note: Left side names showed cytokine dots in the left 4 columns each chip, while right side names showed the right 4 columns part in the same chip. (D) ELISA results of IL-8 in the supernatants of A. pleuropneumoniae 5b WT- or 5b ΔAdh-infected PAMs; (E) JC-1 staining of A. pleuropneumoniae 5b WT- or 5b ΔAdh-infected PAMs; (F) Annexin V/PI of A. pleuropneumoniae 5b WT- or 5b ΔAdh-infected PAMs.

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