Figure 3: Adh-induce apoptosis of PAMs via the activation of Fas. | Scientific Reports

Figure 3: Adh-induce apoptosis of PAMs via the activation of Fas.

From: Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release

Figure 3

(A) Expression of caspase-8 after A. pleuropneumoniae 5b WT or 5b ΔAdh infection; (B) The effects of caspase inhibitors on 5b WT- or 5b ΔAdh-induced apoptosis; (C) qRT-PCR identification results of Fas in 5b WT- or 5b ΔAdh-infected PAMs; (D) Flow cytometry identification results of the expression of Fas in 5b WT- or 5b ΔAdh-infected PAMs; (E,F) The effects of Fas antibody pretreatment on the activation of caspase-3; (G) Flow cytometry results of PAM apoptosis.

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