Figure 6: Screening and identification results of PAM surface Adh-interacting proteins. | Scientific Reports

Figure 6: Screening and identification results of PAM surface Adh-interacting proteins.

From: Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release

Figure 6

(A) Immune co-precipitation results of Adh and the PAM total protein mixture; (B) Laser-scanning confocal microscopy results of suspected proteins expressed on the surface of 293 T cells; (C) Adh adheres to 293 T cells expressing different proteins; (D) A. pleuropneumoniae adhered to different protein-expressing 293 T cells; (E) A. pleuropneumoniae adhered to OR5M11 antibody-pretreated 293 T cells expressing different proteins; (F) OR5M11 antibody pretreatment significantly inhibited A. pleuropneumoniae-induced IL-8 release by PAMs; (G,H) Apoptosis-related proteins expressed in A. pleuropneumoniae-infected and OR5M11 antibody-pretreated PAMs; (I) p53 activation in A. pleuropneumoniae-infected and OR5M11 antibody-pretreated PAMs.

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