Figure 7: A. pleuropneumoniae 5b WT- or 5b ΔAdh-intranasally infected BALB/c mice. | Scientific Reports

Figure 7: A. pleuropneumoniae 5b WT- or 5b ΔAdh-intranasally infected BALB/c mice.

From: Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release

Figure 7

(A) Survival of A. pleuropneumoniae 5b WT- or 5b ΔAdh-infected mice with an infectious dose of 1 × 108 CFU per mouse; (B) bacterial lung burden of A. pleuropneumoniae-infected mice; (C,D) qRT-PCR results for the expression of inflammatory cytokines in A. pleuropneumoniae-infected mice; (E) Lung-apparent pathological changes due to different doses of A. pleuropneumoniae 5b WT or 5b ΔAdh in infected mice; (F) Increased lung weights of 5b WT- or 5b ΔAdh-infected mice at different time points; (G) Total proteins in BALF; (H) H&E staining of lungs; (I) Neutrophils in the lungs (I), MPO in the sera (J) and the bacterial lung burden (K) of G31P-treated mice.

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